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    "doi": "10.1037\/adb0000815",
    "status": "found",
    "title": "Impact of a computerized distress intolerance intervention on electrocortical reactivity to cannabis and threat cues: A randomized controlled trial.",
    "authors": [
        "Richard J. Macatee",
        "Thomas J. Preston",
        "Kaveh Afshar",
        "Norman B. Schmidt",
        "Jesse R. Cougle"
    ],
    "container": "Psychology of Addictive Behaviors",
    "year": "2022",
    "doi_url": "https:\/\/doi.org\/10.1037\/adb0000815",
    "is_open_access": true,
    "oa_status": "hybrid",
    "best_landing_page": "https:\/\/pubmed.ncbi.nlm.nih.gov\/35129994",
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    "abstract": "OBJECTIVE: Given increasing rates of daily cannabis use and Cannabis Use Disorder (CUD) in the United States, it is imperative to understand CUD mechanisms in high-risk groups. Cannabis users with high distress intolerance (DI) are at elevated risk for severe and chronic CUD, but neural mechanisms linking CUD and DI are unknown. Cross-sectional data suggests that acute stress modulation of the cannabis and threat cue-elicited late positive potential (LPP), a neurophysiological marker of motivated attention, are possible mechanisms. However, longitudinal research is needed to clarify the roles of these elicited LPPs in CUD maintenance. METHOD: Sixty cannabis users with high DI were randomized a brief computerized intervention targeting DI or a control intervention. Elicited LPPs were measured before and after a stressor at baseline and postintervention. Intervention effects on stress modulation of the cannabis and threat LPPs, as well as their prospective associations with CUD, were assessed. RESULTS: Elicited LPPs did not significantly change in either intervention group. Acute stress enhancement of the cannabis LPP predicted more severe CUD and greater chronicity at 4-month follow-up. CONCLUSIONS: Cannabis and threat LPPs were not altered by a brief DI intervention despite improvement in DI and cannabis use outcomes. Given that acute stress enhancement of the cannabis LPP predicted poorer CUD outcome, it may be a fruitful intervention target in distress intolerant cannabis users. (PsycInfo Database Record (c) 2022 APA, all rights reserved).",
    "abstract_notice": null,
    "locations": [
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            "source": "Psychology of Addictive Behaviors",
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            "source": "PubMed",
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            "version": "publishedVersion"
        },
        {
            "source": "PubMed Central",
            "landing_page_url": "https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/9357238",
            "pdf_url": null,
            "is_oa": true,
            "version": "submittedVersion"
        }
    ],
    "crossref_links": [
        {
            "url": "http:\/\/psycnet.apa.org\/journals\/adb\/36\/7\/920.pdf",
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    "pubmed_search": "https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=10.1037%2Fadb0000815",
    "google_scholar": "https:\/\/scholar.google.com\/scholar?q=Impact%20of%20a%20computerized%20distress%20intolerance%20intervention%20on%20electrocortical%20reactivity%20to%20cannabis%20and%20threat%20cues%3A%20A%20randomized%20controlled%20trial."
}